Culturomics is defined as the study of human culture and cultural trends through the quantitative analysis of massive amounts of digitized data. Considered as an effective method for humanities computing in the context of Big Data, Culturomics pushes forward the development of Digital Humanities. This paper provides a detailed summary of the studies on Culturomics initially emerging in Science and Nature, and gives a thorough review of its application in the fields such as language change, culture studies, sentiment analysis and future forecasting, in the expectation that more attention will be given to Culturomics in order to capture this new trend in humanities research in the era of Big Data.