Traditional sentence processing theories claim that N400 indexes the difficulty of semantic integration and that P600 reflects the revision of syntactic process. However, it is no longer a tenable proposition with the “semantic P600-effect” triggered by the semantic implausibility, which stirred the curiosity of the academia and a rethink of the neural mechanism of sentence processing. In this paper, six major architectures of sentence interpretation -- Semantic Attraction, Monitoring Theory, Continued Combinatory Analysis, the extended Argument Dependency Model, Processing Competition and Retrieval-Integration -- were reviewed and the neural mechanism and debates concerning N400 and P600 were discussed based on the latest research findings.