Computer assisted language learning has been an increasingly important method to improve university students’ language learning experience. To investigate the factors influencing university students using Web 2.0 applications in foreign language learning, this study proposed a research model on the basis of technology acceptance model. Data were collected from undergraduate students (N = 291) at a university through questionnaire. Subsequent structural equation modeling analysis revealed that perceive usefulness, perceived ease of use, perceived enjoyment and facilitating conditions exerted significant direct positive influence upon behavioral intention. Overall, the proposed model accounted for 75.5% of the variance of behavioral intention.